Highly Regioselective Hydroaminomethylation of Terminal Olefins to Linear Amines Using Rh Complexes with a Tetrabi Phosphorus Ligand.

来源：刘国都教授个人网站发布日期：2019-09-28

作者：Guodu Liu, Kexuan Huang, Chaoxian Cai, Bonan Cao, Mingxin Chang, Wenjun Wu,* Xumu Zhang.*
关键字：regioselective Hydroaminomethylation
论文来源：期刊
具体来源：Chem-Eur. J. 2011, 17, 14559-14563. (DOI: 10.1002/chem.201103073, full paper, IF = 5.160, Citation:
发表时间：2011年

A highly regioselective hydroaminomethylation of terminal olefins catalyzed by Rh complexes with 2, 2′, 6, 6′‐tetrakis ((diphenylphosphino)methyl)‐1, 1′‐biphenyl (Tetrabi) ligand has been

developed. Up to 99?% amine selectivity, 168 linear/branched amine product ratio (n/i), and 97.4?% linear amine yield has been obtained at a substrate/rhodium precursor ratio (S/Rh) of 1000 with this methodology. The turnover number was achieved 6930 at 10000 S/Rh ratio,

and the n/i can reach up to >525. Several different olefins and secondary amines have been applied successfully with high chemoselectivity (99?%), yield (>98?%), and regioselectivity

(>120).

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